Mayo Clinic
2025-09-12 17:01
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Special thanks to Goldman Philanthropic Partnerships for funding this series.
00:00 - Introduction to Follicular Lymphoma
00:40 - Key Questions for Relapsed Lymphoma
02:08 - Treatment Options
02:43 - CAR-T Cell Therapy
03:20 - Bispecific Antibodies
04:00 - Zanabrutinib and Other Options
04:57 - A Personalized Treatment Plan
05:44 - Conclusion and Acknowledgments
Descriptions:
00:00 - Introduction to Follicular Lymphoma
Introduction of Dr. Thomas Witzig from the Mayo Clinic and the topic of discussion: relapsed follicular lymphoma. Brief overview of what follicular lymphoma is and how it typically presents.
00:40 - Key Questions for Diagnosis and Treatment
Outlines the important questions a doctor will ask a patient with relapsed follicular lymphoma.
02:08 - Treatment Options for Relapsed Follicular Lymphoma
Various treatment approaches available, Dr. Witzig explains that options depend on the patient's prior treatments.
02:43 - CAR-T Cell Therapy
CAR-T cell therapy, how a patient's T-cells are genetically modified to specifically target and attack the lymphoma cells, resulting in a high response rate.
03:20 - Bispecific Antibodies
Use of bispecific antibodies as another treatment. These antibodies have two "heads", one that attaches to the tumor and another that attaches to a patient's own T-cells, bringing them together to fight the cancer.
04:00 - Zanabrutinib and Other Options
The combination of the pill zanabrutinib with obinutuzumab. The R² regimen (rituximab and lenalidomide), highlighting its effectiveness as a second-line treatment.
04:57 - A Personalized Approach to Treatment
Personalized treatment plan, doctors will consider the patient's overall health and personal feelings about their disease to create a plan that is right for them.
05:44 - Conclusion and Acknowledgments
The video concludes with a thank you to the patients, the Mayo Clinic team, and the Goldman Philanthropic Partnerships for their support in creating the video series.
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Mayo Clinic
2025-09-12 15:25
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This group education session is designed to help kidney transplant patients learn how to use a National Kidney Registry (NKR) Microsite to support their search for a living donor. Patients are guided through the process of creating and personalizing their own NKR microsite, which serves as a tool to share their story and invite potential donors to come forward. The session includes a live demonstration of how the microsite works, tips for sharing it through social media and email, and strategies for talking about the need for a kidney donor.
0:00 Welcome And NKR Microsites Session Overview
3:24 Meet NKR Coach: Yaretli’s Recipient Story
7:32 Asking For Help Opens Donor Doors
11:41 What Is A Microsite? Key Features
13:46 How Microsites Register And Track Donors
17:52 Craft Story, Photos, And Voucher Coaching
21:58 Business Cards And How To Share
24:04 Setting Up Your Microsite: Fields, Photos
27:08 Team Roles: Admin, Caregiver, And Champion
33:18 Share Your Story: Outreach And Media
37:22 Email Templates, Coaches, And Resource Links
39:26 Voucher Program: Faster Matches And Timing
41:33 Paired Exchange Versus Voucher: Why Voucher
43:39 Mentors Help Register And Share Safely
46:44 Donor Shield Protections: Wages, Travel, Support
48:48 Donor Prioritization Benefit If Ever Needed
52:55 Live Q&A: Microsites, Exchange, And Vouchers
54:59 Coaching Access And Getting Started Help
57:14 Share Your Microsite Link With Confidence
59:18 Closing Remarks And Final Thank You
Visit Mayo Clinic: https://mayocl.in/2COVmlm
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Computerphile
2025-09-12 12:05
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It's an older paper, but it checks out. Rob Miles discusses the problem of 'Sleeper Agents' - where LLMs could have hidden traits we don't know about until it's too late.
Computerphile is supported by Jane Street. Learn more about them (and exciting career opportunities) at: https://jane-st.co/computerphile
This video was filmed and edited by Sean Riley.
Computerphile is a sister project to Brady Haran's Numberphile. More at https://www.bradyharanblog.com
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Kurzgesagt - In a Nutshell
2025-09-10 15:30
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Our first PC game Star Birds is now available in Early Access on Steam! 🚀
We’ve spent over two and a half years working on this with the amazing team at Toukana Interactive, and we’re incredibly proud to finally share it with you.
Join your flock of Star Birds on a mission across the great beyond, establish a thriving mining operation, and discover new technologies to advance even further.
Play it now on Steam: https://kgs.link/sb-ealaunch
Thanks for all your support so far!
This wouldn't have been possible without you! 💖🦆
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Kurzgesagt - In a Nutshell
2025-09-10 15:00
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Play it now on Steam: https://kgs.link/sb-ealaunch
Our first PC game Star Birds is now available in Early Access on Steam! 🚀
We’ve spent over two and a half years working on this with the amazing team at Toukana Interactive, and we’re incredibly proud to finally share it with you.
Join your flock of Star Birds on a mission across the great beyond, establish a thriving mining operation, and discover new technologies to advance even further.
Thanks for all your support so far!
This wouldn't have been possible without you! 💖🦆
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Computerphile
2025-09-05 12:33
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Following on from 'MikeBot3000' we're delving into just how the Generative AI systems create video. Lewis Stuart is based at the University of Nottingham
Computerphile is supported by Jane Street. Learn more about them (and exciting career opportunities) at: https://jane-st.co/computerphile
This video was filmed and edited by Sean Riley.
Computerphile is a sister project to Brady Haran's Numberphile. More at https://www.bradyharanblog.com
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General
Canada RSS Widget
2025-09-12 21:35
COVID cases rising in several provinces. <div><img src="https://i.cbc.ca/1.7632926.1757712484!/fileImage/httpImage/image.jpg_gen/derivatives/...
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<div><img src="https://i.cbc.ca/1.7632926.1757712484!/fileImage/httpImage/image.jpg_gen/derivatives/16x9_1180/wastewater-bottle-for-covid-19-surveillance.jpg?im=Resize=620" style="width: 100%;" /><div>Wastewater and other disease indicators for COVID are beginning to increase in parts of Canada, infectious disease physicians say, as students and teachers return to school and people begin to congregate indoors.</div></div>
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Yahoo Sports
2025-09-12 20:13
Eagles receive troubling injury update on Dallas Goedert. The Philadelphia Eagles will be shorthanded against the Kansas City Chiefs...
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2025-09-12 20:12
Panthers Injury Report & Transactions – Week 2. The Carolina Panthers front office is busy throughout the season with transactions, roster moves, an...
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The Carolina Panthers front office is busy throughout the season with transactions, roster moves, and injury updates. Here’s what’s happening at Mint Street this week. Injury Report The biggest question mark on the injury report as of the time of publication is whether starting left tackle Ikem Ekwonu will see the field. He has been limited every […]
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2025-09-12 20:10
Japan to send ASDF fighter jets to Europe, Canada for 1st time. <div><img src="https://japantoday.com/images/japan-today-social.jpg" style="width: 100%;" /><div>Jap...
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<div><img src="https://japantoday.com/images/japan-today-social.jpg" style="width: 100%;" /><div>Japan will send Air Self-Defense Force F-15 fighter jets for the first time to Britain, Germany and Canada for defense exchanges starting this weekend, Defense Minister Gen Nakatani said Friday. The defense cooperation tour from Sunday, which will last about two weeks excluding joint training, comes amid heightened global tensions.…</div></div>
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Deutsche Welle
2025-09-12 20:09
NATO launches new mission to protect eastern flank. In response to the incursion of Russian drones into Polish airspace, NATO is launching a new operati...
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In response to the incursion of Russian drones into Polish airspace, NATO is launching a new operation called "Eastern Sentry" to protect its members who are vulnerable to Russia.
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NY Times Politics
2025-09-12 19:52
What Charlie Kirk Meant to His Young Supporters. At a memorial outside of the hospital where Charlie Kirk died, mourners described his impact on youn...
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At a memorial outside of the hospital where Charlie Kirk died, mourners described his impact on younger generations.
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